Research shows differing effects from treatment for male, female models One of the many confounding questions about Alzheimer’s disease is why women are at greater risk. Of the approximately 7 million people diagnosed with Alzheimer’s in the United States, nearly two-thirds are women. There are several theories as to why, including that women live longer than men, societal factors, biological factors and more. But the question is far from answered. That gender imbalance may be a significant factor when developing new treatments as well. A recent study from the Hascup Lab at the Smith Alzheimer