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Patients with Hard-to-treat Depression Have Options with Esketamine

As a USPS mail carrier and mother of three, Tricia Duckworth began struggling with depression in her mid-20s. She felt tired, anxious and struggled to find a reason to get out of bed. As her symptoms progressed, she began seeing Karen Broquet, MD, a psychiatrist at SIU Medicine. Through the years, Dr. Broquet and Duckworth tried a variety of drug therapies to treat her depression. Ultimately, she was on the highest allowed dose of Effexor (venlafaxine) and could function on an interim basis. Unfortunately, the side effects were often as challenging as the depression itself. “I was treated with
News

Patients with Hard-to-treat Depression Have Options with Esketamine

As a USPS mail carrier and mother of three, Tricia Duckworth began struggling with depression in her mid-20s. She felt tired, anxious and struggled to find a reason to get out of bed. As her symptoms progressed, she began seeing Karen Broquet, MD, a psychiatrist at SIU Medicine. Through the years, Dr. Broquet and Duckworth tried a variety of drug therapies to treat her depression. Ultimately, she was on the highest allowed dose of Effexor (venlafaxine) and could function on an interim basis. Unfortunately, the side effects were often as challenging as the depression itself. “I was treated with
News

Pandemic tests grit of health care workforce, support systems for physician burnout

Last March, Vidya Sundareshan, MD, was on her first family vacation in more than a year, traveling to San Antonio, Tx., to attend her brother’s wedding. Sundareshan had been named co-chief of the SIU Department of Internal Medicine’s Division of Infectious Diseases (with colleague Vidhya Prakash, MD) on March 1. The trip was a welcome break and an opportunity to tend to her own needs as a busy physician. However, her vibrating phone kept reminding her that multiple health care systems were preparing for the inevitable. The coronavirus outbreak that had been an overseas occurrence before the
News

Pandemic tests grit of health care workforce, support systems for physician burnout

Last March, Vidya Sundareshan, MD, was on her first family vacation in more than a year, traveling to San Antonio, Tx., to attend her brother’s wedding. Sundareshan had been named co-chief of the SIU Department of Internal Medicine’s Division of Infectious Diseases (with colleague Vidhya Prakash, MD) on March 1. The trip was a welcome break and an opportunity to tend to her own needs as a busy physician. However, her vibrating phone kept reminding her that multiple health care systems were preparing for the inevitable. The coronavirus outbreak that had been an overseas occurrence before the
News

SIU researchers track COVID’s impact on dementia

Kevin Hascup, PhD, assistant professor of neurology, recently received funding through an NIH grant to research the link between COVID-19 and cellular senescence and its possible impact on Alzheimer’s disease pathology. The novel coronavirus SARS-CoV-2 (COVID-19), along with respiratory and “flu-like” symptoms, led to an unexpected rise in strokes, brain hemorrhaging, and memory impairment in young (30s and 40s) COVID-19 patients. These phenomena sparked scientific studies of the impact of COVID-19 on the brain, which showed that the virus could infect the brain’s nerve cells, called neurons
News

SIU researchers track COVID’s impact on dementia

Kevin Hascup, PhD, assistant professor of neurology, recently received funding through an NIH grant to research the link between COVID-19 and cellular senescence and its possible impact on Alzheimer’s disease pathology. The novel coronavirus SARS-CoV-2 (COVID-19), along with respiratory and “flu-like” symptoms, led to an unexpected rise in strokes, brain hemorrhaging, and memory impairment in young (30s and 40s) COVID-19 patients. These phenomena sparked scientific studies of the impact of COVID-19 on the brain, which showed that the virus could infect the brain’s nerve cells, called neurons
News

Busy biochemistry lab is mapping virus

A biochemistry laboratory at SIU School of Medicine is sequencing the genomes of SARS-CoV-2 viruses that cause COVID-19 to determine if distinct variants exist in different Illinois communities and specifically in rural versus metropolitan areas. “We’re looking for the ‘personality’ of the genome, to see how it’s changing over time,” says Keith Gagnon, PhD, assistant professor in the Department of Biochemistry and Molecular Biology. “There are a couple of variants and we need to determine which is the most dangerous. Based on what we learn, we can tell the virus’ point of origin, whether it’s
News

Busy biochemistry lab is mapping virus

A biochemistry laboratory at SIU School of Medicine is sequencing the genomes of SARS-CoV-2 viruses that cause COVID-19 to determine if distinct variants exist in different Illinois communities and specifically in rural versus metropolitan areas. “We’re looking for the ‘personality’ of the genome, to see how it’s changing over time,” says Keith Gagnon, PhD, assistant professor in the Department of Biochemistry and Molecular Biology. “There are a couple of variants and we need to determine which is the most dangerous. Based on what we learn, we can tell the virus’ point of origin, whether it’s
News

Busy biochemistry lab is mapping virus

A biochemistry laboratory at SIU School of Medicine is sequencing the genomes of SARS-CoV-2 viruses that cause COVID-19 to determine if distinct variants exist in different Illinois communities and specifically in rural versus metropolitan areas. “We’re looking for the ‘personality’ of the genome, to see how it’s changing over time,” says Keith Gagnon, PhD, assistant professor in the Department of Biochemistry and Molecular Biology. “There are a couple of variants and we need to determine which is the most dangerous. Based on what we learn, we can tell the virus’ point of origin, whether it’s
News

Lab students step up, test up

The global pandemic has exposed some vulnerabilities within the American health care system that should surprise no one: International travel bans can disrupt supply lines. Fragmented health systems can lead to bidding wars for scarce resources. A lack of testing capability limits the effectiveness of any public health response. Amidst these systemic pitfalls, here’s a bit of good news. SIU School of Medicine has been collaborating with the Illinois Department of Public Health (IDPH) to overcome another looming problem: a national shortfall in skilled lab workers. In 2001 the Centers for
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