Combined Drug Therapies May Prevent Need for Surgery A new clinical trial for bladder cancer has opened exclusively at Southern Illinois University School of Medicine in Springfield. The trial will combine the current use of drug therapy placed inside the bladder with a new, intravenous drug that increases the response of the immune system. The study will determine if the combination of the two drugs is safe and potentially be more effective at eliminating the cancer cells. The new drug, pembrolizumab, may fight the disease and prevent the need for surgery. Dr. Shaheen Alanee, assistant