Trial
Psychiatry

ImpactTD Registry: A prospective multicenter study to characterize the natural history of tardive dyskinesia (TD) and investigate the real-world effectiveness of deutetrabenazine on the multidimensional impact of TD

Active recruiting

TV50717-CNS-40223: The purpose of this study is to get a better understanding of the disease course of tardive dyskinesia and the impact it has on individuals’ lives. In subjects who may begin on deutetrabenazine (AUSTEDO®) treatment during the study, it will also help investigate the real-world effectiveness of this treatment, particularly on a person’s quality of life.

Trial
Psychiatry

Click: Study to Evaluate the Efficacy and Safety of a Digital Therapeutic as an Adjunct to Standard-of-Care Antipsychotic Therapy in Adult and Late Adolescent Participants with Experiential Negative Symptoms of Schizophrenia

Active recruiting

CT-155-R-001: The purpose of this study is to investigate if digital therapeutics (a moblie software application) can help treat certain symptoms of schizophrenia. 

Trial
Neurology

A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

Active recruiting

The primary objective is to assess the effect of XEN1101 versus placebo on reducing PGTCS frequency in subjects with PGTCS.

Trial
Neurology

A Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 3 Study to Evaluate the Safety, Tolerability, and Efficacy of XEN1101 as Adjunctive Therapy in Focal-Onset Seizures

Active recruiting

The primary objective of this study is to assess the effect of XEN1101 versus placebo on reducing focal seizure frequency.

Trial
Neurology

An Open-Label, Multicenter, Outpatient Extension Study to Evaluate the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older with Stereotypical Prolonged Seizures

Active recruiting

The primary endpoint of this study is to evaluate the long-term safety and tolerability of Staccato alprazolam.

Trial
Neurology

A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Outpatient, Parallel-Group Study to Assess the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older with Stereotypical Prolonged Seizures

Active recruiting

The purpose of this study is to compare the success of a single admnistration of Staccato alprazolam compared with placebo in rapidly terminating a seizure episode within 90seconds after IMP administration.

News

Durbin visits Simmons Cancer Institute to discuss nationwide shortage of cancer drugs

Senator Dick Durbin held a news conference at SIU's Simmons Cancer Institute to discuss the shortage of life-saving drugs for cancer patients. Last month, Durbin urged the FDA to use the agency’s authority to immediately address the ongoing shortage.
News

Durbin visits Simmons Cancer Institute to discuss nationwide shortage of cancer drugs

Senator Dick Durbin held a news conference at SIU's Simmons Cancer Institute to discuss the shortage of life-saving drugs for cancer patients. Last month, Durbin urged the FDA to use the agency’s authority to immediately address the ongoing shortage.
News

Durbin visits Simmons Cancer Institute to discuss nationwide shortage of cancer drugs

Senator Dick Durbin held a news conference at SIU's Simmons Cancer Institute to discuss the shortage of life-saving drugs for cancer patients. Last month, Durbin urged the FDA to use the agency’s authority to immediately address the ongoing shortage.
News

Durbin visits Simmons Cancer Institute to discuss nationwide shortage of cancer drugs

Senator Dick Durbin held a news conference at SIU's Simmons Cancer Institute to discuss the shortage of life-saving drugs for cancer patients. Last month, Durbin urged the FDA to use the agency’s authority to immediately address the ongoing shortage.
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