Diagnosis for Amyloid Heart Disease: Cardiac amyloidosis can do undiagnosed or misdiagnosed for years as it can mimic other conditions. Cardiac amyloidosis is a progressive disease and early diagnosis is critical in altering the course of the disease. It is important to talk to specialists in the field if you have symptoms of amyloidosis like congestive heart failure, shortness of breath, irregular heart rhythm, neuropathy, unexplained stroke, swelling of legs or ankles, or kidney dysfunction. SIU Medicine specialists use the following tests to arrive at the correct diagnosis: 1. Detailed