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News

A healthier bladder

An estimated 25 million American adults experience urinary incontinence, which is the involuntary loss of urine from the bladder or the inability to control urination. While this group of conditions can affect anyone, urinary incontinence is most common in women older than 50. As area leaders in urology care and research, our multidisciplinary team at SIU Medicine has helped thousands of women throughout the region find answers and relief from their bladder concerns. Types of urinary incontinence and its symptoms Several types of urinary incontinence exist, including urge incontinence (being

News

A hidden danger of cookout season

As the summer cookout season heats up, here’s a cautionary tale about a potential danger of cleaning your grill. On a warm June evening in Springfield, the Keuchlers – Candi, William and 5-year-old daughter Neela – were enjoying a chicken wing dinner fresh from the family grill when Neela’s eyes suddenly widened in alarm. “I can’t swallow,” she said. She wasn’t choking, but hives began to break out on the child’s neck. A quick flashlight inspection of Neela’s mouth revealed the culprit. A wire bristle had lodged horizontally in her throat. It had come off the grill-cleaning brush and adhered

News

A morning skincare routine that works

Because I’m an SIU Medicine dermatologist with a specific skin type (oily), you might think I use fancy and expensive products. The truth is my skincare routine is much simpler than what I tend to see on social media. I can find everything I need from big box stores (superstores) or the local drugstore. Here's what I do every morning to protect and nourish my skin: 1. Wash with a gentle, fragrance-free cleanser Since I shower in the morning, I simply complete this first step right in the shower. I always use a gentle, fragrance-free cleanser with simple ingredients that removes sebum, makeup

News

A new prenatal care option for high-risk moms-to-be

Pregnancy is an exciting period for the expectant mother, and one which requires lifestyle changes and a heightened focus on well-being. Obstetric practices in the U.S. typically require at least 12 in-person pre- and post-natal office visits for the mom-to-be to have adequate preparation for a safe delivery and what comes after. In cases when a complication occurs, the care team may consult a Maternal-Fetal Medicine physician, also known as a high-risk obstetrician. Unfortunately, not all expectant mothers have easy access to prenatal care, due to location, economics or transportation. For

Trial

Psychiatry

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Valbenazine as Adjunctive Treatment in Subjects with Schizophrenia

Active recruiting

The primary objective for this study is to evaluate the effect of adjunctive valbenazine versus placebo on symptoms of schizophrenia in subjects who have inadequate response to antipsychotic treatment.

Trial

Simmons Cancer Institute

A Phase 3, Randomized, Open-Label Study to Evaluate Safety and Efficacy of Epcoritamab in Combination With R-CHOP Compared to R-CHOP in Subjects With Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)

Active recruiting

The purpose of this study is to assess the change in disease activity of epcoritamab when combined with intravenous and oral rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine, and prednisone (R-CHOP) or R-CHOP in adult participants globally with diffuse large b-cell lymphoma (DLBCL).

Trial

Simmons Cancer Institute

A Phase II Open-Label Study of Sacituzumab Govitecan in Unresectable Locally Advanced/Metastatic Urothelial Cancer

Active recruiting

The objective of this study is to evaluate the efficacy and safety of sacituzumab govitecan-hziy monotherapy and with novel combinations in participants with metastatic urothelial cancer (mUC).

News

A physiatrist: What to expect

Physiatry is a clinical specialty that focuses on optimizing the function and quality of life in people with a wide range of physical impairments, disabilities and conditions. It’s also known as physical medicine and rehabilitation (PM&R). How could this branch of medicine help you or your loved one manage a health condition? Physiatrists, sometimes called PM&R physicians, diagnose and treat medical conditions caused by injury, illness, or disease affecting the nervous system (brain, spinal cord, nerves) and musculoskeletal system (bones, joints, ligaments, muscles, and tendons). Conditions

Trial

Psychiatry

A PRospective, Multi-cEnter, Randomized Controlled Blinded Trial DemOnstrating the Safety and Effectiveness of VNS Therapy® System as AdjunctivE Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression (RECOVER)

Active recruiting

The primary objective of this study is to determine whether active VNS Therapy treatment is superior to a no stimulation control in producing at least a 50% reduction in baseline depressive symptom severity, based on Montgomery Åsberg Depression Rating Scale (MADRS) total score, at 12 months from randomization.

Trial

Psychiatry

A prospective multicenter study to characterize the natural history of tardive dyskinesia (TD) and investigate the real-world effectiveness of deutetrabenazine on the multidimensional impact of TD

Active recruiting

What is the effectiveness of deutetrabenazine treatment on the multidimensional impact of TD movements on individuals’ lives?

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